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Cancer Clinical Trials

Site: Hematologic/Blood-Related

The most recent listing of current clinical trials for hematologic and blood-related cancers — including blood and marrow transplant/BMT, leukemia, non-Hodgkins lymphoma, Hodgkin's disease/lymphoma and multiple myeloma — appears below. Should you be interested in learning more about any of these clinical trials, please use our Contact Us form.
 

Site: Hematologic/Blood-Related
(Includes Blood and Marrow Transplant/BMT,
Leukemia, Non-Hodgkins Lymphoma,
Hodgkin's Disease/Lymphoma,
Lymphoma and Multiple Myeloma)

Protocol ID    Title

C-205    Phase IIB, Multicenter, Randomized, Open-Label trial of CPX-351 (Cytarabine: Daunorubicin) Liposome Injection v. Intensive Salvage Therapy in Adult Patients < 60 Years Old with AML in First Relapse Following an Initial CR > 1 Month Duration

Keywords: AML in First Relapse Following an Initial CR > 1 Month Duration

C10403    An Intergroup Phase II Clinical Trial of Adolecents and Young Adults with Untreated Acute Lymphoblastic Leukemia

Keywords: Adolecents and Young Adults with Untreated Acute Lymphoblastic Leukemia

In-House    Skin Biopsy and Use of Normal Donor Apheresis Product in Laboratory Validation Studies

Keywords: skin biopsy

In-House    Haploidentical Hematopoietic Stem Cell Transplantation (HCT) Using Highly Purified Hematopoietic Stem Cells

Keywords: haploidentical hematopoietic stem cell transplantation

In-House    Laboratory Studies of Iron Metabolism in Blood Cells from Patients with Hematochromatosis

Keywords: patients with hematochromatosis

In-House    Pre-Clinical Evaluation of Gallium Compounds in Chronic Lymphocytic Leukemia

Keywords: chronic lymphocytic leukemia (CLL)

FH 1803.00    Donor Lymphocyte Infusion for the Treatment of Malignancy After Hematopoietic Cell Transplantation Using Nonmyeloablative Conditioning - A Multi-Center Trial

Keywords: after hematopoitic cell transplantation

FH 1813.00    A Multi-Center Phase III Study Comparing Nonmyeloablative Conditioning with TBI versus Fludarabine/TBI for HLA-Matched Related Hematopoietic Cell Transplantation for Treatment of Hematologic Malignancies

Keywords: HLA-Matched Related Hematopoietic Cell Transplantation for Treatment of Hematologic Malignancies

FH 1938.00    A Randomized Phase III Study to Determine the Most Promising Post grafting Immunosuppression for Prevention of Acute GVHD after Unrelated Donor G-CSF Mobilized Peripheral Blood Mononuclear Cell (G-PBMC) Transplantation Using Nonmyeloablative Conditioning for Patients with Hematologic Malignancies: A Multi-Center Trial

Keywords: after Unrelated Donor G-CSF Mobilized Peripheral Blood Mononuclear Cell (G-PBMC) Transplantation

FH 2054.00    Cyclophosphamide and Antithymocyte Globulin Conditioning Regimen for Marrow Transplantation from HLA-Matched Family Members for Severe Aplastic Anemia: Effect of Marrow Cell Dose on Chronic Graft-vs. Host Disease: A Multi-Center Trial

Keywords: Severe Aplastic Anemia

FH 2239.00    Transplantation of Unrelated Donor Umbilical Cord Blood in Patients with Hematologic Malignancies Using Reduced -Intensity Preparative Regimen

Keywords: Transplantation of Unrelated Donor Umbilical Cord Blood in Patients with Hematologic Malignancies

U of M    A Multicenter, Prospective Trial to Evaluate the Role of NK Cell Kir Epitope Mismatch on Mortality and Disease Relapse in T-Cell Depleted Hematopoietic Stem Cell Transplantation from HLA-C Mismatched, Unrelated Donors for Myeloid Malignancies

Keywords: hematopoietic stem cell transplants and myeloid malignancies

In-House:EBV Auto    A Study of Cellular Adoptive Immunotherapy as Treatment for EBV-LPD; Use of Autologous Epstein Barr Virus Specific Cytotoxic T-Lymphoctyes

Keywords: Treatment for Epstein Barr Virus

In-House: T-Cell    A Single Arm, Phase II Trial of Transplantation of HLA-Identical Sibling, CD34+ Enriched, Peripheral Blood Stem Cells Isolated by the Isolex System with a Fixed T-Cell Dose in the Treatment of Patients with Hematologic Malignancies

Keywords: Hematologic Malignancies

In-House: Pre-Clinical
Vaccine for MM
   Pre-Clinical Studies on Vaccine Derived From Patient-Derived Myeloma Cells

Keywords: Multiple Myeloma

In-House Zometa    A Randomized Phase II Study of Zoledronic Acid (Zometa ®) in the Prevention of Osteoporosis in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Keywords: allogenic hematopoietic stem cell transplant

In-House: Technetium    Development of 99m Technetium Scanning as a Quantitative in Vivo Assay to Predict Chemotherapy Drug Resistance and Clinical Outcome in Lymphoma Patients

Keywords: Lymphoma

Seattle 1992.00    A Multi-Center Phase III Study Comparing Myeloablative to Nonmyeloablative Transplant Conditioning in Patients with Myelodysplastic Syndrome or Acute Myelogenous Leukemia

Keywords: Myelodysplastic Syndrome or Acute Myelogenous Leukemia

Washington University    A Phase II Multicenter Study of Lenalidomide in Relapsed or Refractory Classical Hodgkin Lymphoma

Keywords: Relapsed or Refractory Classical Hodgkin Lymphoma

SCOT    A Randomized , Open label, Phase II/III Multicenter Study of High-Dose Immunosuppressive Therapy Using Total Body Irradiation, Cyclophosphamide, ATGAM, and Autologous Transplantation with Auto-CD34+HPC Versus Intravenous Pulse Cyclophosphamide for the Treatment of Severe Systemic Sclerosis

Keywords: Severe Systemic Sclerosis

CIBMTR 07-REV    Evaluation of Lenalidominde as Maintenance Therapy Post Allogeneic Hematopoietic Cell Transplantation for High-Risk Multiple Myeloma

Keywords: Post Allogeneic Hematopoietic Cell Transplantation for High-Risk Multiple Myeloma

NMDP/ CIBMTR    The Financial Impact of Allogeneic Stem Cell Transplantation on Patient and Family: A Pilot Study

Keywords: Financial Impact of Allogeneic Stem Cell Transplantation

Industry AML/ALL    A Phase II Study of SCH 727965 in Subjects with Relapsed and Refractory Acute Myelogenous Leukemia and Acute Lymphoblastic Leukemia

Keywords: Relapsed and Refractory Acute Myelogenous Leukemia and Acute Lymphoblastic Leukemia

Jak 2    A Randomized, Double-Blind, Placebo-Controlled Study of the JAK Inhibitor INCB018424 Tablets Administered Orally to Subjects with Primary Myelofibrosis (PMF), Post-Polycythemia Vera- Myelofibrosis (PPV-MF) or Post Essential Thrombocythemia-Myelofibrosis (PET-MF)

Keywords: Primary Myelofibrosis (PMF), Post-Polycythemia Vera- Myelofibrosis (PPV-MF) or Post Essential Thrombocythemia-Myelofibrosis (PET-MF)

FH 2184.00    Chronic GVHD Protocol: Improving Outcomes Assessment in Chronic GVHD

Keywords: Chronic GVHD

In-House: Haplo-Cord    Phase II Study: Myeloablative Human Stem Cell Transplant (HSCT) Using Selected Mismatched Related Donor and One Umbilical Cord Unit

Keywords: Human Stem Cell Transplant

S0521    A Randomized Trial of Maintenance v. Observation for Patients with Previously Untreated Low and Intermediate Risk Acute Promyelocytic Leukemia (APL), Phase II

Keywords: Previously Untreated Low and Intermediate Risk Acute Promyelocytic Leukemia (APL)

E2903    Phase II Trial of Pentostatin, Cyclophosphamide and Rituximab (PCR) Followed by Campath-1H for Previously Treated Relapsed or Refractory Patients with Chronic Lymphocytic Leukemia

Keywords: Previously Treated Relapsed or Refractory Patients with Chronic Lymphocytic Leukemia

E2905    Randomized Phase III Trial Comparing the Frequency of Major Erythroid Response (MER) to Treatment with Lenalidomide (Revlimid ®) Alone in Combination with Epoetin Alfa (Procrit ®) in Subjects with Low- or Intermediate -1 Risk MDS and Symptomatic Anemia

Keywords: Low- or Intermediate -1 Risk MDS and Symptomatic Anemia

Industry 095    An International, Multicenter, Open-Label Study of Vorinostat (MK-0683) in Combination with Bortezomib in Patients with Relapsed and Refractory Multiple Myeloma

Keywords: Patients with Relapsed and Refractory Multiple Myeloma

 

 

Last Review Date: Nov. 18, 2009

Online Editor(s): Richard Petre

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