| Protocol ID |
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Title |
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| CTN-0303 |
|
A Single Arm, Multicenter Phase II Trial of Transplants of HLA-Matched, CD34 + Enriched, T Cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients with AML (Acute Myelogenous Leukemia) in First or Second Morphologic Complete Remission
Keywords: AML (Acute Myelogenous Leukemia) in first or second morphologic complete remission |
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| Industry-AML |
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A Phase III Randomized, Double-Blind, Controlled Study Comparing Clofarabine and Cytarabine v. Cytarabine Alone in Adult Patients >= 60 Years Old with Acute Myelogenous Leukemia (AML) who have Relapsed or are Refractory after Receiving up to Two Prior Induction Regimens
Keywords: adult patients >= 60 years old with acute myelogenous leukemia (AML) who have relapsed or are refractory after receiving up to 2 prior induction regimens |
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| In-House |
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Skin Biopsy and Use of Otherwise Discarded Cellular Material for Laboratory Validation
Keywords: skin biopsy |
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| In-House |
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Skin Biopsy and Use of Normal Donor Apheresis Product in Laboratory Validation Studies
Keywords: skin biopsy |
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| In-House |
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Kinetics of the Immune Response to Aspergillus Post Hematopoietic Progenitor Cell Transplantation
Keywords: post hematopoietic progenitor cell transplantation |
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| Industry-280 |
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A Phase III, Randomized, Double Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Prochymal (Ex-vivo Cultured Adult Human Mesenchymal Stem Cells) Infusion for the Treatment of Steroid- Refractory Acute GVHD
Keywords: steroid-refractory acute GVHD |
|
| In-House |
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Haploidentical Hematopoietic Stem Cell Transplantation (HCT) Using Highly Purified Hematopoietic Stem Cells
Keywords: haploidentical hematopoietic stem cell transplantation |
|
| In-House |
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Laboratory Studies of Iron Metabolism in Blood Cells from Patients with Hematochromatosis
Keywords: patients with hematochromatosis |
|
| In-House |
|
Pre-Clinical Evaluation of Gallium Compounds in Chronic Lymphocytic Leukemia
Keywords: chronic lymphocytic leukemia (CLL) |
|
| FH 1591.00 |
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Campath {Alemtuzumab} Dose Escalation, Low-Dose TBI and Fludarabine Followed by HLA Class I Mismatched Donor Stem Cell Transplantation for Patients with Hematologic Malignancies-A Multi-Center Trial
Keywords: hematologic malignancies |
|
| FH 1803.00 |
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Donor Lymphocyte Infusion for the Treatment of Malignancy After Hematopoietic Cell Transplantation Using Nonmyeloablative Conditioning - A Multi-Center Trial
Keywords: after hematopoitic cell transplantation |
|
| FH 1813.00 |
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A Multi-Center Phase III Study Comparing Nonmyeloablative Conditioning with TBI versus Fludarabine/TBI for HLA-Matched Related Hematopoietic Cell Transplantation for Treatment of Hematologic Malignancies
Keywords: HLA-Matched Related Hematopoietic Cell Transplantation for Treatment of Hematologic Malignancies |
|
| FH 1938.00 |
|
A Randomized Phase III Study to Determine the Most Promising Post grafting Immunosuppression for Prevention of Acute GVHD after Unrelated Donor G-CSF Mobilized Peripheral Blood Mononuclear Cell (G-PBMC) Transplantation Using Nonmyeloablative Conditioning for Patients with Hematologic Malignancies: A Multi-Center Trial
Keywords: after Unrelated Donor G-CSF Mobilized Peripheral Blood Mononuclear Cell (G-PBMC) Transplantation |
|
| FH 2054.00 |
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Cyclophosphamide and Antithymocyte Globulin Conditioning Regimen for Marrow Transplantation from HLA-Matched Family Members for Severe Aplastic Anemia: Effect of Marrow Cell Dose on Chronic Graft-vs. Host Disease: A Multi-Center Trial
Keywords: Severe Aplastic Anemia |
|
| U of M |
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A Multicenter, Prospective Trial to Evaluate the Role of NK Cell Kir Epitope Mismatch on Mortality and Disease Relapse in T-Cell Depleted Hematopoietic Stem Cell Transplantation from HLA-C Mismatched, Unrelated Donors for Myeloid Malignancies
Keywords: hematopoietic stem cell transplants and myeloid malignancies |
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| In-House:EBV Auto |
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A Study of Cellular Adoptive Immunotherapy as Treatment for EBV-LPD; Use of Autologous Epstein Barr Virus Specific Cytotoxic T-Lymphoctyes
Keywords: Treatment for Epstein Barr Virus |
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| In-House: T-Cell |
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A Single Arm, Phase II Trial of Transplantation of HLA-Identical Sibling, CD34+ Enriched, Peripheral Blood Stem Cells Isolated by the Isolex System with a Fixed T-Cell Dose in the Treatment of Patients with Hematologic Malignancies
Keywords: Hematologic Malignancies |
|
| E2902 |
|
A Phase III Randomized Study of Farnesyl Transferase Inhibitor R115777 in Acute Myeloid Leukemia (AML) Patients in Second or Subsequent Remission or in Remission After Primary Induction Failure
Keywords: Acute Myeloid Leukemia (AML) Patients in Second or Subsequent Remission or in Remission After Primary Induction Failure |
|
| E5998 |
|
A Phase II Study of Initial Treatment with Methotrexate in Large Granular Lymphocytic (LGL) Leukemia
Keywords: Large Granular Lymphocytic (LGL) Leukemia |
|
| E4402 |
|
Randomized Phase III Trial Comparing Two Different Rituximab Dosing Regimens for Patients with Low Tumor Burden Indolent Non-Hodgkin's Lymphoma
Keywords: Patients with Low Tumor Burden Indolent Non-Hodgkin's Lymphoma |
|
| C100104 |
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A Phase III Randomized, Double-Blind Study of Maintenance Therapy with CC-5013 (NSC #703813, IND #70116) or Placebo Following Autologous Stem Cell Transplantation for Multiple Myeloma
Keywords: Multiple Myeloma |
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| Industry-NHL |
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A Randomized, Open-Label, Multicenter Study of VELCADE with Rituximab or Rituximab Alone in Subjects with Relapsed or Refractory, Rituximab Naïve or Sensitive Follicular B-Cell Non-Hodgkin's Lymphoma
Keywords: Relapsed or Refractory, Rituximab Naïve or Sensitive Follicular B-Cell Non-Hodgkin's Lymphoma |
|
| Industry-transplant |
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Compassionate Use Protocol for the use of AMD3100 to Mobilize Peripheral Blood Stem Cells for the Collection and Transplantation
Keywords: transplantation |
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In-House: Pre-Clinical
Vaccine for MM |
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Pre-Clinical Studies on Vaccine Derived From Patient-Derived Myeloma Cells
Keywords: Multiple Myeloma |
|
| In-House |
|
A Randomized Phase II Study of Zoledronic Acid (Zometa ®) in the Prevention of Osteoporosis in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Keywords: allogenic hematopoietic stem cell transplant |
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| In-House: Technetium |
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Development of 99m Technetium Scanning as a Quantitative in Vivo Assay to Predict Chemotherapy Drug Resistance and Clinical Outcome in Lymphoma Patients
Keywords: Lymphoma |
|
| AVF4064g |
|
A Randomized, Blinded, Placebo Controlled, Multicenter, Phase II Study of Bevcizumab in Combination with Bortezomib Compared with Bortezomib in Patients with Relapsed or Refractory Multiple Myeloma
Keywords: Relapsed or Refractory Multiple Myeloma |
|
| E3402 |
|
A Phase II Trial of R-CHOP Followed by Zevalin Radioimmunotherapy for Patients with Previously Untreated Stages I and II CD20+ Diffuse Large Cell Non-Hodgkin's Lymphoma
Keywords: diffuse large cell non-Hodgkin’s lymphoma |
|
| E1405 |
|
A Phase II study of VcR-CVAD with Rituximab Maintenance for Untreated Mantle Cell Lymphoma
Keywords: Untreated Mantle Cell Lymphoma |
|
| E3404 |
|
Response-Adapted Therapy for Aggressive Non-Hodgkin's Lymphoma based on Early (18F) FDG-PET Scanning
Keywords: Non-Hodgkin's Lymphoma |
|
| CTN-0401 |
|
Phase III Rituxan/ BEAM vs. Bexxar/ BEAM with Autologous Hematopoietic Stem Cell Transplantation (ASCT) for Persistent or Relapsed Chemotherapy Sensitive Diffuse Large B-Cell Non-Hodgkin's Lymphoma
Keywords: Persistent or Relapsed Chemotherapy Sensitive Diffuse Large B-Cell Non-Hodgkin's Lymphoma |
|
| Millennium C05008 |
|
Phase I/II Study of VELCADE (Bortezomib), Dexamethasone, and Revlimid (VDCR) in Subjects with Previously Untreated Multiple Myeloma
Keywords: Previously Untreated Multiple Myeloma |
|
| S0106 |
|
A Phase III Study of the Addition of Gemtuzumab Ozogamicin (Mylotarg) During Induction Therapy Versus Standard Induction with Daunomycin and Cytosine Arabinoside Followed by Consolidation and Subsequent Randomization to Post-Consolidation Therapy with Gemtuzumab Ozogamicin (Mylotarg) or no Additional Therapy for Patients Under Age 61 with Previously Untreated DeNovo Acute Myeloid Luekemia
Keywords: Patients Under Age 61 with Previously Untreated DeNovo Acute Myeloid Luekemia |
|
| S9007 |
|
Cytogenetic Studies in Leukemia Patients
Keywords: Leukemia |
|
| S9910 |
|
Leukemia Centralized Reference Laboratories and Tissue Repositories
Keywords: Leukemia |
|
| S0325 |
|
A Phase IIB Study of Molecular Responses to Imatinib, at Standard or Increased Doses, or Dasatinib (BMS-354825) (NSC-732517) for Previously Untreated Patients with Chronic Myelogenous Leukemia (CML) in Chronic Phase
Keywords: Previously Untreated Patients with Chronic Myelogenous Leukemia (CML) in Chronic Phase |
|
| SCOT |
|
A Randomized , Open label, Phase II/III Multicenter Study of High-Dose Immunosuppressive Therapy Using Total Body Irradiation, Cyclophosphamide, ATGAM, and Autologous Transplantation with Auto-CD34+HPC Versus Intravenous Pulse Cyclophosphamide for the Treatment of Severe Systemic Sclerosis
Keywords: Severe Systemic Sclerosis |
|