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Stroke/Neurovascular Clinical Trials
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Neurosciences Clinical Trials
Category: Stroke/Neurovascular
The most recent listing of current clinical trials for stroke and neurovascular disorders appears below. Should you be interested in learning more about any of these clinical trials, please use our Contact Us form.
Learn more about the Stroke and Neurovascular Program.
Category: Stroke/Neurovascular
Title
A Randomized Multicenter Clinical Trial of Unruptured Brain AVMs (ARUBA)
Keywords
Brain, Arteriovenous Malformation
Title
Interventional Management of Stroke Trial III
Keywords
Stroke, Intervention
Title
Stenting and Agressive Medical Management for Preventing Recurrent Stroke in Interacranial Stenosis
Keywords
Recurrent Stroke, Intracranial Stenosis, Stents
Title
Vitesse Intracranial Stent Study for Ischemic Therapy
Keywords
Intracranial, Stent, Ischemia
Title
Secondary Prevention of Small Subcortical Strokes.
In small subcortical stroke patients: Hypertensive patients will be treated to different BP targets using commonly prescribed medications. Aspirin combined with clopidogrel will be tested to learn if these medications used together are more effective than asprin alone in preventing strokes.
Keywords
Subcortical stroke, Stroke, Hypertension, Aspirin, Clopidogrel, Prevention
Title
Insulin Resistance Intervention after Stroke or TIA.
This study is designed to determine if a medication called pioglitazone is effective in preventing future strokes in patients who do not have diabetes but have suffered a stroke and also have insulin resistance.
Keywords
Stroke, insulin resistance, TIA, pioglitazone, Prevention
Title
Specific Phonological Therapy in Fluent Aphasia
Keywords
Aphasia, Speech Therapy
Title
Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS)
The purpose of this study is to see what is the best way to prevent a stroke in a person with narrowed arteries in their brain. A narrowed artery may slow or stop the blood from flowing to the brain. The study will compare two types of treatments: medical therapy only (such as controlling your blood pressure, controlling high cholesterol and quitting smoking) or medical therapy plus opening the blocked blood vessel with balloon angioplasty and stent (a balloon which is inflated in the artery pushes the plaque to the side of the artery and a stent is a small mesh tube that helps keep the blood vessel open.) More information on how the stent works in the narrowed artery over a longer period of time (3 years) will be collected. The research results will be used to help determine which type of therapy is better at preventing a stroke. This study is being conducted nationally. Osama Zaidat, MD, MSc is the principle investigator at Froedtert & The Medical College of Wisconsin.
Keywords
Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis
Title
Secondary Prevention of Small Subcortical Strokes (SPS3)
This study aims to prevent a second stroke in patients who have had a lacunar stroke (a stroke that occurs in the inner part of the brain when small blood vessels become blocked). The study is determining if aspirin and Clopidogrel (Plavix) are better than aspirin alone to prevent a second stroke and if keeping blood pressure low will help to prevent a second stroke. Diane Book, MD, is the principle investigator at Froedtert & The Medical College of Wisconsin.
Keywords
Secondary Prevention of Small Subcortical Strokes
Title
Insulin Resistance Intervention after Stroke (IRIS)
This multi-center study of the National Institutes of Health aims at treating patients with insulin resistance in the hope it will help to prevent diabetes and a second ischemic stroke. A medication (approved by the FDA for controlling diabetes) or a placebo is given to patients who have had an ischemic stroke or transient ischemic attack and are insulin resistant. Michel Torbey, MD, MPH, FAHA, is the principle investigator at Froedtert & The Medical College of Wisconsin.
Keywords
Insulin Resistance Intervention after Stroke
Title
Albumin in Acute Stroke Trial: A Trial of High-Dose Albumin Therapy for Neuroprotection in Acute Ischemic Stroke (ALIAS)
This study is to evaluate the effectiveness of high-dose, intravenous human serum albumin in the treatment of ischemic stroke within 5 hours of stroke onset. In animal laboratory studies, it has been shown to reduce the size of infarction in the brain and improve neurological function after stroke, and also decrease or eliminate brain swelling that may occur. About 60 sites will enroll participants worldwide. Michel Torbey, MD, MPH, FAHA, is the principle investigator at Froedtert & The Medical College of Wisconsin.
Keywords
Albumin in Acute Stroke Trial
Title
Interventional Management of Stroke (IMS III)
This multi-center study of the National Institutes of Health is for patients within three hours of symptom onset of an acute ischemic stroke. The study is comparing treatment with intravenous tissue plasminogen activator (IV tPA, the standard FDA approved treatment) to a combination of IV tPA plus intra-arterial tPA administered via a small catheter directly into the blocked artery within the brain. Froedtert & The Medical College of Wisconsin have the only program in Wisconsin participating in this study. Osama Zaidat, MD, MSc, is the principle investigator at Froedtert & The Medical College.
Keywords
Interventional Management of Stroke
Title
Stroke Warning Information and Faster Treatment Study (SWIFT)
Keywords
stroke, interactive educational program, acute ischemic stroke
Title
Imaging Guided Patient Selection for Interventional Revascularization Therapy
Keywords
stroke, cerebral vessel occlusion, Penumbra System, intracerebral hemorrhage, NIHSS
Title
Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage
Keywords
ventricular hemorrhage thrombolysis
Last Review Date: Feb. 25, 2010 Online Editor(s): Richard Petre |
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