An Exploratory Study of Neoadjuvant Endocrine Therapy in Hormone Receptor-Positive HER2-Negative Node-Negative Breast Cancer Patients to Assess Responses and Mechanisms of Endocrine Resistance

Protocol No
IIT-CHAUDHARY-ENDOCRINE
Principal Investigator
Lubna Chaudhary
Phase
II
Summary
In this study, we want to see if tumor based biomarkers have a connection to disease response with anti-estrogen therapy. Biomarkers are part of the tumor cells and their levels in the tumor tissue may have a relationship with treatment response. We plan to look at your tissue samples before and after your anti-estrogen therapy for research purposes. We would like to see if these biomarker levels might help predict treatment response in the future. The purpose is not to discover information that could be used to change your medical care or make a change to your diagnosis.
Description
Endocrine therapy before surgery to assess disease response and mechanisms of resistance in tumor cells
Participating Institutions
Froedtert West Bend Hospital
Froedtert Menomonee Falls Hospital
Froedtert Hospital
Status
CLOSED TO ACCRUAL
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