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Genomically-Guided Treatment Trial in Brain Metastases

Protocol No
Principal Investigator
Fernando Santos Pinheiro
This study is being done to answer the following question: Can anticancer therapies help to treat cancer that has spread to the brain? The purpose of this study is to test good and bad effects of different drugs against metastatic brain tumors with altered genes. This trial is trying to see if tumor genetic testing would be helpful at guiding treatment in patients such as you. Researchers have looked at the DNA material (genes) that can be affected in brain metastases and have found several genes that are altered, or mutated. There are medications that target these genes. We are doing this study because we want to find out if this approach is better or worse than the usual approach for your metastatic cancer. The usual approach is defined as care most people get for your metastatic cancer.
Genetic Testing in Guiding Treatment for Patients With Brain Metastases
Participating Institutions
Froedtert Hospital