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A Multicenter, Pivotal Phase 3 Study of Iomab-B Prior to Allogeneic Hematopoietic Cell Transplantation versus Conventional Care in Older Subjects with Active, Relapsed or Refractory Acute Myeloid Leukemia

Protocol No
ACTINIUM-SIERRA-IOMAB-01
Principal Investigator
Parameswaran Hari
Phase
III
Summary
The purpose of this study is to test the efficacy (effectiveness), tolerability and safety of targeted radiation delivered by radiolabeled antibody (protein made in the body in response to foreign substance), followed by a bone marrow stem cell transplant. This study will look at the effects, good or bad, that this combined treatment has on the body and leukemia.
Description
Study of Iomab-B Prior to HCT vs Conventinal Care in Older Stubjects with Active R/R AML (SIERRA)
Participating Institutions
Froedtert Hospital
Status
OPEN TO ACCRUAL