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Optimizing Immunosuppression for Steroid-Refractory Anti-PD-1/PD-L1 Pneumonitis

Protocol No
ECOG-EAQ172
Principal Investigator
Jonathan Thompson
Phase
II
Summary
This study is being done to answer the following question: Can treatment with either infliximab or Intravenous Immunoglobulin (IVIG) result in improvement in pneumonitis in patients whose pneumonitis has not improved with corticosteroids? We are doing this study because we want to find out if this approach is better or worse than the usual approach for the management of pneumonitis. We also want to find out if either infliximab or IVIG will help patients with pneumonitis that is not improving with corticosteroids.
Description
Improving the Treatment of Immunotherapy-related Lung Inflammation in Patients where Corticosteroids are No Longer Effective
Participating Institutions
Froedtert Hospital
Status
OPEN TO ACCRUAL
Sub Category