Treatment Free Remission After Combination Therapy with Ruxolitinib Plus Tyrosine Kinase Inhibitors in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation

Protocol No
HJKC3-0002
Principal Investigator
Ehab Atallah
Phase
II
Summary
Recently, clinical trials have looked at patients who are attempting to stop TKI medications for a second time after relapsing during their first stopping attempt. These studies have shown that it is possible to stop a second time and be monitored for recurrence. The purpose of this study is to determine if adding ruxolitinib to a TKI prior to a second attempt at stopping a TKI will lead to prolonged treatment free remission.
Description
Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase Inhibitors
Participating Institutions
Froedtert Hospital
Status
OPEN TO ACCRUAL
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