During a TIPS procedure, a shunt or stent (mesh tube) is passed down the jugular vein (the vein above the collarbone in the neck) using fluoroscopy (real time x-rays) guidance. The stent then is inserted between the portal vein (vein that carries blood from the intestines into the liver) to a hepatic vein (vein that carries blood away from the liver back to the heart). This means that blood that would usually go to the intestinal veins is now going to the heart. Because more blood will be flowing to the heart, the heart needs to be strong enough to handle the extra volume.
This study is being done to determine the impact of the TIPS procedure on cardiac (heart) function by collecting data (heart pressures) during the TIPS procedure. Immediately after TIPS and at standard follow-up time points, labs and transthoracic echocardiograms (TTE or echo) will also be collected.
Primary Investigator: Eric J. Hohenwalter, MD
Sub-Investigators: Michael Cinquegrani, MD; Aiman Ghufran, MD; Robert A. Hieb, MD; Johnny Hong, MD; Kim Joohyun, MD, PhD; Parag J. Patel, MD, MS; Kaila Redifer Tremblay, MD; William Rilling, MD; Kia Saeian, MD, MS; Matthew Scheidt, MD; Achuthan Sourianarayanane, MD; Sean M. Tutton, MD; Sarah B. White, MD, MS
ClinicalTrials.gov Identifier: NCT04050683