A Phase 2, Open-Label, Randomized, Multicenter Study to Evaluate the Safety and Efficacy of Axatilimab in Combination with Ruxolitinib in Participants with Newly Diagnosed Chronic Graft-Versus-Host Disease

Protocol No
INCYTE-INCA-34176-254
Staff Member
Mehdi Hamadani
Phase
II
Summary

This project is being done to evaluate the safety, tolerability, and preliminary activity of axatilimab in combination with ruxolitinib and to assess the contribution of axatilimab to the combination treatment effect in participants with cGVHD.
Objective
A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease
Study Sites
Froedtert Hospital
Status
OPEN TO ACCRUAL
Categories
Cancer, Multiple Myeloma, Leukemia, Hematologic/Blood Related Cancers
ClinicalTrials.gov
https://www.clinicaltrials.gov/study/NCT06388564