Memory Disorders Clinical Translational Science (MD-CTS) Team 

The MD-CTS Team was established in early 2018 and is focused on conducting research that has immediate translational potential to our patients with mild cognitive impairment (MCI) and dementia.  We have integrated cognitive neuroimaging on hundreds of patients with neurodegenerative conditions thus far and have accumulated detailed cognitive data on over 100 patients diagnosed with MCI (amnestic and non-amnestic subtypes) who have had cognitive neuroimaging including volumetric measures and DTI within 1 year of their comprehensive neuropsychological evaluation as part of scheduled clinical visits.

MD-CTS efforts have accounted for 10 well-received posters or presentations at national and international conferences detailing our scientific and translational work; several manuscripts are under preparation. Grant-funded research will commence (Drs. Umfleet and Agarwal, PIs) that examines the potentiating effects of cerebrovascular disease on MCI (amnestic and non-amnestic subtypes).  

A pilot study is currently recruiting patients with the logopenic variant of Primary Progressive Aphasia (lvPPA), a condition that is also known as the language form of Alzheimer’s disease. Our study seeks to investigate the therapeutic potential of High Definition transcranial direct current stimulation (HD-tDCS), a novel, safe, and noninvasive form of brain stimulation, in patients afflicted by this condition (Dr. Granadillo, PI). https://clinicaltrials.gov/ct2/show/NCT03805659 

Research team members include:

  • Alissa Butts, PhD
  • Julie Janecek, PhD
  • Barb Blaney, Supervisor/Research Coordinator
  • Karen Schmidt, Research Nurse
  • Peter Kraegel, Psychometrics/ Research Coordinator
  • Shelby Schold, Research Assistant
  • Malgorzata Franczak, MD (director of MD-CTS)
  • Laura Umfleet, PsyD (co-director of MD-CTS)
  • Elias Granadillo, MD
  • Piero G. Antuono, MD
     

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