Learn more about clinical trials basics and early-phase clinical trials, as well as some of the unique features our research program, including our Translational Research Unit
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Melanoma Margins Trial (MelMarT): A Phase III, Multi-Centre, Multi-National Randomised Control Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma
Testing a narrower margin in surgery for patients with primary cutaneous melanoma
We are doing this study because we want to find out if this approach is better or worse than the usual approach for melanoma surgery. The usual approach is defined as care most people get for melanoma.
We are doing this study because we want to find out if this approach is better or worse than the usual approach for melanoma surgery. The usual approach is defined as care most people get for melanoma.
Protocol No
SWOG-S2015
Categories
An Open-Label, Navigational Investigation of Profile-Related Evidence Determining Individualized Cancer Therapy for Patients with Aggressive Malignancies and Poor Prognoses
IIT-GEORGE-I-PREDICT
Protocol No
IIT-GEORGE-I-PREDICT
Categories
Cancer,
Colorectal,
Early Phase/Multiple Disease Site Cancers,
Thoracic Cancers,
Sarcoma,
Skin Cancers,
Prostate and Urologic Cancers,
Head and Neck Cancers,
Gynecologic Cancers,
Gastrointestinal Cancers,
Breast Cancers,
Lung,
Esophagus,
Melanoma, Skin,
Other Urologic,
Bladder,
Lip, Oral Cavity and Pharynx,
Larynx,
Ovary,
Other Gastrointestinal,
Stomach,
Pancreas/Liver,
Esophagus
Inhibition of Oral Tumorigenesis by Antitumor B
IIT-WONG-ATB-RANDOMIZED
Protocol No
IIT-WONG-ATB-RANDOMIZED
Categories
Randomized COVID-19 Testing in Vulnerable Communities and Risk Tool Creation
Novel Methods For Estimating True Covid-19 Infection Rates And Progression Risks
Protocol No
IIT-MEURER-NIH-COVIDMKE
Categories
Expanded Access IND Protocol: Use of Tecovirimat (TPOXX) for Treatment of Human Orthopoxvirus Infections (CDC IND 116039, CDC IRB Protocol #6402)
TPOXX for Treatment of Human Orthopoxvirus Infections
Protocol No
INF-CDC-TPOXX-EA-IND-MONKEYPOX
Categories
A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants With Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)
Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN) (SANCTUARY)
Protocol No
NEPH-ALEXION-ALXN1210-202
Categories
A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of the Safety and Efficacy
of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS - IGAN)
Study of the Safety and Efficacy of OMS721 in Patients With Immunoglobulin A (IgA) Nephropathy
Protocol No
NEPH-ELMEANAWY-OMEROS2
Categories
Cerebrovascular Reactivity in Adults on Hemodialysis and Intradialytic Cerebral Perfusion
Cerebrovascular Reactivity in Dialysis Patients
Protocol No
NEPH-IIT-WOLFGRAM-CRHP
Categories
A Pivotal Phase 3 Trial To Evaluate The Safety And Efficacy Of Clazakizumab For The Treatment Of Chronic Active Antibody-Mediated Rejection In Kidney Transplant Recipients
Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients
Protocol No
NEPH-SAAD-IMAGINE
Categories
Effectiveness of Switching to Cladribine Tablets in Multiple Sclerosis Patients with High Disease Activity or Disease Breakthrough in a US Real-World Population (HDA Switch Study)
Cladribine Tablets in MS with High Disease Activity or Disease Breakthrough
Protocol No
NEURO-EMD-HDA-SWITCH