All of Us Research Program
Do you want to change the future of health? The Froedtert & MCW health network is part of the National Institutes of Health All of Us Research Program. It has a simple mission — speed up health research breakthroughs. To do this, All of Us is asking one million people to share their health information. Learn how you can help make a difference by joining the All of Us Research Program.
Cladribine Tablets: Collaborative Study to Evaluate Impact On Central Nervous System Biomarkers in Multiple Sclerosis (CLOCK-MS)
The purpose of this research study is to better understand how cladribine works in patients with RMS by looking at the effect of the medication on biomarkers in the central nervous system (CNS) and blood that are known to be important in RMS.
Parkinson’s Foundation PD GENEration Genetic Registry
Radicava®/(Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)
A Phase 3b, Multicenter, Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Oral Edaravone Administered for a Period of 48 Weeks in Subjects with Amyotrophic Lateral Sclerosis (ALS)
NeuroMuscular ObserVational Research (“MOVR Data Hub”)
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Clinical Trial to Evaluate the Tolerability, Safety, and Efficacy of PRAX-944 in the Treatment of Adults with Essential Tremor
A Phase 2, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of SAR443820 in adult participants with amyotrophic lateral sclerosis, followed by an open-label extension
A Phase 3, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Reldesemtiv in Patients with Amyotrophic Lateral Sclerosis (ALS)
An Observational Study Using Multimodal Sensors to Measure Cognitive Health in Adults and Distinguish Mild Cognitive Impairment From Normal Aging
Statins Use in Intracerebral Hemorrhage Patients (SATURN)
Anticoagulation in Intracerebral Hemorrhage (ICH) Survivors for Stroke Prevention and Recovery (ASPIRE)
A Phase 3b, Multicenter, Open-label Study to Evaluate the Immune Response to, and the Safety of, Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Oral Ozanimod Compared to Non-pegylated Interferon (IFN)-β or No Disease Modifying Therapy
This project is being done to learn how ozanimod impacts the body’s immune system responds to vaccines in subjects with relapsing multiple sclerosis (MS).
CorEvitas SPHERES (Synergy of Prospective Health and Experimental Research for Emerging Solutions) Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD)
This project is being done to learn more about NMOSD, how doctors treat NMOSD, how well medications and other treatments work, the safety of those treatments, and to improve the care and outcomes of people with NMOSD.
A Multicenter, Longitudinal, Open-Label, Single-Arm Study Describing Cognitive Processing Speed Changes in Relapsing Multiple Sclerosis Subjects Treated With Ozanimod (RPC-1063)
This project is being done to learn about changes in cognition that happen while being treated with Ozanimod.
A Phase III Multicenter Randomized, Double-Blind, Double-Dummy, Parallel-Group Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Adult Patients With Relapsing Multiple Sclerosis
This project is being done to compare the effects, good or bad, of fenebrutinib versus teriflunomide on patients with RMS.
A Phase III Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group Study to Evaluate the Efficacy and Safety Of Fenebrutinib Compared With Ocrelizumab in Adult Patients With Primary Progressive Multiple Sclerosis
This project is being done to compare the effects of fenebrutinib versus ocrelizumab on patients with PPMS.
A Study of Suboptimally Controlled Participants Previously Taking Oral or Infusion DMDs for RMS
This project is being done to understand how well patients respond to cladribine tablets. This is an observational study.
The purpose of this study is to determine if the study drug called ALZ-801 is safe, if it is well tolerated, and if it is effective in treating AD. It is a twice a day oral medication that is taken with meals.
The purpose of this study is to learn more about the use of the study drug, simufilam, for the treatment of Alzheimer’s disease. We want to test that it is safe and to find out whether it can slow down the advance of Alzheimer’s disease.
This project is being done to determine if the experimental drug AL001 is effective and safe in treating individuals who have a known progranulin gene mutation that causes FTD, when compared to placebo (a solution that contains no active AL001 drug).