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Learn more about clinical trials basics and early-phase clinical trials, as well as some of the unique features our research program, including our Translational Research Unit. Froedtert & MCW health network is also part of the National Institutes of Health All of Us Research Program.  

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A Phase IIIb Study to Characterize the Efficacy and Safety of Adjuvant Ribociclib Plus Endocrine Therapy in a Close-to-Clinical Practice Patient Population With HR+ HER2- Early Breast Cancer

Objective
The purpose of this open-label, multicenter, phase IIIb, single-arm study is to characterize the efficacy and safety of the combination of ribociclib and standard adjuvant endocrine therapy on invasive breast cancer-free survival, in a close to clinical practice patient population with HR-positive, HER2-negative, early breast cancer.
Protocol No
NOVARTIS-CLEE011O12001-WIDER
Categories

A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Patients With Endocrine-Resistant Hormone

Objective
A study to evaluate the efficacy and safety of triplet combination of inavolisib plus ribociclib and fulvestrant versus placebo plus ribociclib and fulvestrant in the first-line setting in participants with endocrine-therapy-resistant hormone receptor positive, human epidermal growth factor receptor 2-negative advanced breast cancer.
Protocol No
HOFFMAN-LAROCHE-CO46274
Categories