A Phase 1/2, Open-Label Study of PD-1 Knockout Tumor-Infiltrating Lymphocytes (IOV-4001) in Participants with Unresectable or Metastatic Melanoma or Stage III or IV Non-Small-Cell Lung Cancer

Protocol No

IOVANCE-IOV-GM1-201

Phase

I/II

Summary

This project is being done to find out whether the investigational drug, called IOV-4001, is safe and beneficial in the treatment of patients with unresectable or metastatic melanoma or advanced Non-Small Cell Lung Cancer (NSCLC).

Description

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

Participating Institutions

Froedtert Hospital

Status

OPEN TO ACCRUAL